Item Type | Name |
Academic Article
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Lovastatin enhances clearance of apoptotic cells (efferocytosis) with implications for chronic obstructive pulmonary disease.
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Academic Article
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Surface enhanced laser desorption/ionization (SELDI) time-of-flight mass spectrometry to identify patients with chronic obstructive pulmonary disease.
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Academic Article
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The role of oxidative stress in chronic obstructive pulmonary disease.
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Academic Article
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Cigarette smoke decreases MARCO expression in macrophages: implication in Mycoplasma pneumoniae infection.
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Academic Article
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Superoxide dismutase 3 polymorphism associated with reduced lung function in two large populations.
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Academic Article
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Finding Needles in the Haystack: The Search for Plasma Biomarkers for COPD.
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Academic Article
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beta2-agonists promote host defense against bacterial infection in primary human bronchial epithelial cells.
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Academic Article
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Family factors are associated with psychological distress and smoking status in chronic obstructive pulmonary disease.
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Academic Article
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Bronchial secretory immunoglobulin a deficiency correlates with airway inflammation and progression of chronic obstructive pulmonary disease.
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Academic Article
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Plasma antioxidants are associated with impaired lung function and COPD exacerbations in smokers.
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Academic Article
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Gender differences of airway dimensions in anatomically matched sites on CT in smokers.
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Academic Article
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Cigarette smoke decreases airway epithelial FABP5 expression and promotes Pseudomonas aeruginosa infection.
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Academic Article
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Role of IL-18 in second-hand smoke-induced emphysema.
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Academic Article
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Differences in adjustment between individuals with alpha-1 antitrypsin deficiency (AATD)-associated COPD and non-AATD COPD.
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Academic Article
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N-acetylcysteine and exacerbations of chronic obstructive pulmonary disease.
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Academic Article
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Endogenous enzymes (NOX and ECSOD) regulate smoke-induced oxidative stress.
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Academic Article
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Smoking reduces surfactant protein D and phospholipids in patients with and without chronic obstructive pulmonary disease.
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Academic Article
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Cigarette smoke impairs clearance of apoptotic cells through oxidant-dependent activation of RhoA.
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Academic Article
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Up-regulation of MUC18 in airway epithelial cells by IL-13: implications in bacterial adherence.
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Academic Article
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Family relationship quality is associated with psychological distress, dyspnea, and quality of life in COPD.
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Academic Article
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Cigarette smoke modulates PGE(2) and host defence against Moraxella catarrhalis infection in human airway epithelial cells.
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Academic Article
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Attributions about cause of illness in chronic obstructive pulmonary disease.
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Academic Article
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Smoking and COPD increase sputum levels of extracellular superoxide dismutase.
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Academic Article
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Chronic obstructive pulmonary disease exacerbations in the COPDGene study: associated radiologic phenotypes.
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Academic Article
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COPD is associated with production of autoantibodies to a broad spectrum of self-antigens, correlative with disease phenotype.
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Academic Article
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A combined pulmonary-radiology workshop for visual evaluation of COPD: study design, chest CT findings and concordance with quantitative evaluation.
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Academic Article
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Automated telecommunication to obtain longitudinal follow-up in a multicenter cross-sectional COPD study.
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Academic Article
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Pulmonary arterial enlargement and acute exacerbations of COPD.
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Academic Article
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Surfactant protein D as a biomarker for chronic obstructive pulmonary disease.
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Academic Article
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Human neutrophil elastase degrades SPLUNC1 and impairs airway epithelial defense against bacteria.
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Concept
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Pulmonary Disease, Chronic Obstructive
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Concept
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Chronic Disease
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Academic Article
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Endothelial cell adhesion molecule CD146: implications for its role in the pathogenesis of COPD.
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Academic Article
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Peripheral blood mononuclear cell gene expression in chronic obstructive pulmonary disease.
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Academic Article
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The association of adiponectin with computed tomography phenotypes in chronic obstructive pulmonary disease.
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Academic Article
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Integrative omics approach identifies interleukin-16 as a biomarker of emphysema.
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Academic Article
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Assessment of two immunodepletion methods: off-target effects and variations in immunodepletion efficiency may confound plasma proteomics.
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Academic Article
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Analysis of the plasma proteome in COPD: Novel low abundance proteins reflect the severity of lung remodeling.
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Academic Article
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Cluster analysis in the COPDGene study identifies subtypes of smokers with distinct patterns of airway disease and emphysema.
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Academic Article
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Circulating hematopoietic progenitor cells are decreased in COPD.
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Academic Article
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Analyzing networks of phenotypes in complex diseases: methodology and applications in COPD.
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Academic Article
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The multiMiR R package and database: integration of microRNA-target interactions along with their disease and drug associations.
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Academic Article
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Prediction of acute respiratory disease in current and former smokers with and without COPD.
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Academic Article
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Pneumothorax risk factors in smokers with and without chronic obstructive pulmonary disease.
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Academic Article
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Non-emphysematous chronic obstructive pulmonary disease is associated with diabetes mellitus.
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Academic Article
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Menthol cigarette smoking in the COPDGene cohort: relationship with COPD, comorbidities and CT metrics.
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Academic Article
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Plasma sphingolipids associated with chronic obstructive pulmonary disease phenotypes.
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Academic Article
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IREB2 and GALC are associated with pulmonary artery enlargement in chronic obstructive pulmonary disease.
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Academic Article
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Relationships between diffusing capacity for carbon monoxide (DLCO), and quantitative computed tomography measurements and visual assessment for chronic obstructive pulmonary disease.
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Academic Article
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Secondhand Tobacco Smoke and COPD Risk in Smokers: A COPDGene Study Cohort Subgroup Analysis.
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Academic Article
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Reduced Bone Density and Vertebral Fractures in Smokers. Men and COPD Patients at Increased Risk.
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Academic Article
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Identifying cases of undiagnosed, clinically significant COPD in primary care: qualitative insight from patients in the target population.
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Academic Article
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Smoking-Associated Site-Specific Differential Methylation in Buccal Mucosa in the COPDGene Study.
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Academic Article
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Significance of Medication History at the Time of Entry into the COPDGene Study: Relationship with Exacerbation and CT Metrics.
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Academic Article
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Clinical and Radiologic Disease in Smokers With Normal Spirometry.
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Academic Article
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Circulating soluble receptor for advanced glycation end products (sRAGE) as a biomarker of emphysema and the RAGE axis in the lung.
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Academic Article
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Rationale and Design of the Genomic Research in Alpha-1 Antitrypsin Deficiency and Sarcoidosis Study. Alpha-1 Protocol.
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Academic Article
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Right ventricular diastolic function and exercise capacity in COPD.
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Academic Article
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COPD subtypes identified by network-based clustering of blood gene expression.
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Academic Article
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Risk factors for COPD exacerbations in inhaled medication users: the COPDGene study biannual longitudinal follow-up prospective cohort.
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Academic Article
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Inflammatory triggers associated with exacerbations of COPD orchestrate plasticity of group 2 innate lymphoid cells in the lungs.
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Academic Article
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Association between Functional Small Airway Disease and FEV1 Decline in Chronic Obstructive Pulmonary Disease.
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Academic Article
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Common Genetic Polymorphisms Influence Blood Biomarker Measurements in COPD.
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Academic Article
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A New Approach for Identifying Patients with Undiagnosed Chronic Obstructive Pulmonary Disease.
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Academic Article
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Quantitative computed tomography measurements to evaluate airway disease in chronic obstructive pulmonary disease: Relationship to physiological measurements, clinical index and visual assessment of airway disease.
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Academic Article
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Biomarkers of extracellular matrix turnover are associated with emphysema and eosinophilic-bronchitis in COPD.
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Academic Article
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Acute Exacerbations and Lung Function Loss in Smokers with and without Chronic Obstructive Pulmonary Disease.
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Academic Article
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Respiratory Symptoms Items from the COPD Assessment Test Identify Ever-Smokers with Preserved Lung Function at Higher Risk for Poor Respiratory Outcomes. An Analysis of the Subpopulations and Intermediate Outcome Measures in COPD Study Cohort.
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Academic Article
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Gene and metabolite time-course response to cigarette smoking in mouse lung and plasma.
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Academic Article
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Multiple biomarkers predict disease severity, progression and mortality in COPD.
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Academic Article
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Do COPD subtypes really exist? COPD heterogeneity and clustering in 10 independent cohorts.
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Academic Article
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Frequency of exacerbations in patients with chronic obstructive pulmonary disease: an analysis of the SPIROMICS cohort.
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Academic Article
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Meta-analysis of peripheral blood gene expression modules for COPD phenotypes.
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Academic Article
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The value of blood cytokines and chemokines in assessing COPD.
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Academic Article
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Handgrip Strength in Chronic Obstructive Pulmonary Disease. Associations with Acute Exacerbations and Body Composition.
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Academic Article
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Systemic Markers of Adaptive and Innate Immunity Are Associated with Chronic Obstructive Pulmonary Disease Severity and Spirometric Disease Progression.
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Academic Article
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Electronic Cigarette Use in US Adults at Risk for or with COPD: Analysis from Two Observational Cohorts.
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Academic Article
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Association of thrombocytosis with COPD morbidity: the SPIROMICS and COPDGene cohorts.
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Academic Article
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Subjective cognitive complaints and neuropsychological performance in former smokers with and without chronic obstructive pulmonary disease.
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Academic Article
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Features of COPD as Predictors of Lung?Cancer.
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Academic Article
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CT measurements of central pulmonary vasculature as predictors of severe exacerbation in COPD.
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Academic Article
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Pectoralis muscle area and mortality in smokers without airflow obstruction.
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Academic Article
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Lower serum IgA is associated with COPD exacerbation risk in SPIROMICS.
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Academic Article
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CT-based Visual Classification of Emphysema: Association with Mortality in the COPDGene Study.
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Academic Article
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Significance of Low-Attenuation Cluster Analysis on Quantitative CT in the Evaluation of Chronic Obstructive Pulmonary Disease.
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Academic Article
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Interstitial Features at Chest CT Enhance the Deleterious Effects of Emphysema in the COPDGene Cohort.
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Academic Article
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NT-proBNP in stable COPD and future exacerbation risk: Analysis of the SPIROMICS cohort.
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Academic Article
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Response.
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Academic Article
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An airway epithelial IL-17A response signature identifies a steroid-unresponsive COPD patient subgroup.
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Academic Article
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Elevated circulating MMP-9 is linked to increased COPD exacerbation risk in SPIROMICS and COPDGene.
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Academic Article
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Bayesian inference of networks across multiple sample groups and data types.
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Academic Article
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Aspirin Use and Respiratory Morbidity in COPD: A Propensity Score-Matched Analysis in Subpopulations and Intermediate Outcome Measures in COPD Study.
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Academic Article
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Systemic Markers of Inflammation in Smokers With Symptoms Despite Preserved?Spirometry in SPIROMICS.
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Academic Article
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Safety and Tolerability of Comprehensive Research Bronchoscopy in Chronic Obstructive Pulmonary Disease. Results from the SPIROMICS Bronchoscopy Substudy.
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Academic Article
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Bioactive Sphingolipids in the Pathogenesis of Chronic Obstructive Pulmonary Disease.
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Academic Article
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Omics and the Search for Blood Biomarkers in Chronic Obstructive Pulmonary Disease. Insights from COPDGene.
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Academic Article
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Genetic Advances in Chronic Obstructive Pulmonary Disease. Insights from COPDGene.
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Academic Article
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A Genetic Risk Score Associated with Chronic Obstructive Pulmonary Disease Susceptibility and Lung Structure on Computed Tomography.
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Academic Article
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Real-world use of rescue inhaler sensors, electronic symptom questionnaires and physical activity monitors in COPD.
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Academic Article
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Clinical Epidemiology of COPD: Insights From 10 Years of the COPDGene Study.
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Academic Article
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Diffusing Capacity of Carbon Monoxide in?Assessment of COPD.
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Academic Article
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Serum amino acid concentrations and clinical outcomes in smokers: SPIROMICS metabolomics study.
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Academic Article
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Radiographic lung volumes predict progression to COPD in smokers with preserved spirometry in SPIROMICS.
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Academic Article
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Reduced Attention in Former Smokers with and without COPD.
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Academic Article
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Pulmonary artery enlargement and mortality risk in moderate to severe COPD: results from COPDGene.
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Academic Article
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Association of urine mitochondrial DNA with clinical measures of COPD in the SPIROMICS cohort.
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Academic Article
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Clinical Significance of Bronchodilator Responsiveness Evaluated by Forced Vital Capacity in COPD: SPIROMICS Cohort Analysis.
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Academic Article
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Carotid Artery Stiffness is Associated With Cognitive Performance in Former Smokers With and Without Chronic Obstructive Pulmonary Disease.
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Academic Article
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Machine Learning and Prediction of All-Cause Mortality in COPD.
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Academic Article
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IGSF3 mutation identified in patient with severe COPD alters cell function and motility.
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Academic Article
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Lung-Specific Risk Factors Associated With Incident Hip Fracture in Current and Former Smokers.
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Academic Article
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Distinguishing Smoking-Related Lung Disease Phenotypes Via Imaging and Molecular Features.
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Academic Article
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Daily Activities: The Impact of COPD and Cognitive Dysfunction.
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Academic Article
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Protein Biomarkers for COPD Outcomes.
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Academic Article
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Soluble receptor for advanced glycation end products (sRAGE) as a biomarker of COPD.
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Academic Article
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Cognitive performance is lower among individuals with overlap syndrome than in individuals with COPD or obstructive sleep apnea alone: association with carotid artery stiffness.
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Academic Article
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Pulmonary Artery Enlargement Is Associated with Exacerbations and Mortality in Ever-Smokers with Preserved Ratio Impaired Spirometry.
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Academic Article
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Multi-omics subtyping pipeline for chronic obstructive pulmonary disease.
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Academic Article
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PaIRKAT: A pathway integrated regression-based kernel association test with applications to metabolomics and COPD phenotypes.
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Academic Article
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Lung Microbiota and Metabolites Collectively Associate with Clinical Outcomes in Milder Stage Chronic Obstructive Pulmonary Disease.
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Academic Article
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Quantitative Interstitial Abnormality Progression and Outcomes in the Genetic Epidemiology of COPD and Pittsburgh Lung Screening Study Cohorts.
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Academic Article
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Diffusing Capacity and Mortality in Chronic Obstructive Pulmonary Disease.
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Academic Article
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Lung Imaging in COPD Part 2: Emerging Concepts.
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Academic Article
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Lung Imaging in COPD Part 1: Clinical Usefulness.
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Academic Article
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Ratio of FEV1/Slow Vital Capacity of?< 0.7 Is Associated With Clinical, Functional, and Radiologic Features of Obstructive Lung Disease in Smokers With Preserved Lung Function.
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Academic Article
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Associations Among 25-Hydroxyvitamin D?Levels, Lung Function, and Exacerbation Outcomes in COPD: An Analysis of the SPIROMICS Cohort.
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Academic Article
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Identification of Sputum Biomarkers Predictive of Pulmonary Exacerbations in COPD.
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Academic Article
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Prolonged, physiologically relevant nicotine concentrations in the airways of smokers.
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Academic Article
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Clinical Implications of Low Absolute Blood Eosinophil Count in the SPIROMICS COPD Cohort.
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Academic Article
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Increased airway iron parameters and risk for exacerbation in COPD: an analysis from SPIROMICS.
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Academic Article
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Significance of FEV3/FEV6 in Recognition of Early Airway Disease in Smokers at Risk of Development of COPD: Analysis of the SPIROMICS Cohort.
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Academic Article
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Bronchodilator Responsiveness in Tobacco-Exposed People With or Without COPD.
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Academic Article
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Racial Segregation and Respiratory Outcomes among Urban Black Residents with and at Risk of Chronic Obstructive Pulmonary Disease.
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Academic Article
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Reconsidering the Utility of Race-Specific Lung Function Prediction Equations.
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Academic Article
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Genetic and non-genetic factors affecting the expression of COVID-19-relevant genes in the large airway epithelium.
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Academic Article
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Association of plasma mitochondrial DNA with COPD severity and progression in the SPIROMICS cohort.
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Academic Article
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Risk of COPD exacerbation is increased by poor sleep quality and modified by social adversity.
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Academic Article
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Current smoking with or without chronic bronchitis is independently associated with goblet cell hyperplasia in healthy smokers and COPD subjects.
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Academic Article
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Lung microbiota associations with clinical features of COPD in the SPIROMICS cohort.
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Academic Article
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Comparative Impact of Depressive Symptoms and FEV1% on Chronic Obstructive Pulmonary Disease.
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Academic Article
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Clinical Phenotypes of Atopy and Asthma in COPD: A Meta-analysis of SPIROMICS and COPDGene.
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Academic Article
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Clustering-based COPD subtypes have distinct longitudinal outcomes and multi-omics biomarkers.
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Academic Article
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Association of Systemic Inflammation with Depressive Symptoms in Individuals with COPD.
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Academic Article
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Genetic variation in genes regulating skeletal muscle regeneration and tissue remodelling associated with weight loss in chronic obstructive pulmonary disease.
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Academic Article
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Comparison of Proteomic Assessment Methods in Multiple Cohort Studies.
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Academic Article
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Mucus Plugs and Emphysema in the Pathophysiology of Airflow Obstruction and Hypoxemia in Smokers.
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Academic Article
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Transcriptomic Signature of Asthma-Chronic Obstructive Pulmonary Disease Overlap in Whole Blood.
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Academic Article
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Hedgehog interacting protein-expressing lung fibroblasts suppress lymphocytic inflammation in mice.
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Academic Article
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Contribution of Individual and Neighborhood Factors to Racial Disparities in Respiratory Outcomes.
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Academic Article
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Defining Resilience to Smoking-related Lung Disease: A Modified Delphi Approach from SPIROMICS.
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Academic Article
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The influence of social support on COPD outcomes mediated by depression.
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Academic Article
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Deep learning on graphs for multi-omics classification of COPD.
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Academic Article
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Causes of and Clinical Features Associated with Death in Tobacco Cigarette Users by Lung Function Impairment.
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Academic Article
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Systemic Markers of Lung Function and Forced Expiratory Volume in 1 Second Decline across Diverse Cohorts.
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Academic Article
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Blood Gene Expression and Immune Cell Subtypes Associated with Chronic Obstructive Pulmonary Disease Exacerbations.
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Academic Article
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A blood and bronchoalveolar lavage protein signature of rapid FEV1 decline in smoking-associated COPD.
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Academic Article
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Bilirubin-associated single nucleotide polymorphism (SNP) and respiratory health outcomes: a mendelian randomization study.
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Academic Article
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Longitudinal Follow-Up of Participants With Tobacco Exposure and Preserved Spirometry.
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Academic Article
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Blood-based Transcriptomic and Proteomic Biomarkers of Emphysema.
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Academic Article
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Pulmonary emphysema subtypes defined by unsupervised machine learning on CT scans.
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Academic Article
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Plasma metabolomics and quantitative interstitial abnormalities in ever-smokers.
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Academic Article
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Noncoding SNPs decrease expression of FABP5 during COPD exacerbations.
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